特兰胺酸给药对外周切除术期间手术期间流血的影响:单中心回顾性观察性研究
Daiki Shirasu1, Masahiko Tsuchiya2, Noriaki Oomae2
1Kishiwada Tokushukai Hospital, Emergency and Critical Care Center, 4-27-1 Kamori-Cho, Kishiwada, Osaka, 596-0042, Japan. shirasu_kpum@yahoo.co.jp.
JA clinical reports
|June 22, 2023
概括
特兰胺酸显著降低了因伪乳瘤和腹膜扩散而经历重大腹部手术的患者的手术内流血. 这种抗纤维解质剂还降低了在这些复杂的手术过程中对输血的需求.
科学领域:
- 在瘤学瘤学.
- 手术创新 在外科创新.
- 药理学 药理学是指药理学的学科.
背景情况:
- 在主要的腹部手术中,特兰胺酸的有效性仍在调查中.
- 对于伪瘤和癌症扩散的腹膜切除涉及大量的血液损失.
研究的目的:
- 为了评估特兰胺酸对手术内流血的作用.
- 评估其对经过腹膜切除的患者输血需求的影响.
主要方法:
- 单中心回顾性观察性研究.
- 包括年龄≥20岁,经过腹切除的患者.
- 酸组 (1000毫克) 与对照组之间的比较.
主要成果:
- 特兰胺酸组的内科手术期间血流量显著降低 (907毫升 vs 1372毫升).
- 在三胺酸组 (1560毫升 vs 2040毫升) 观察到血液输血量减少.
- 经手术后的D-二聚合物水平较低,在三胺酸组中观察到.
结论:
- 特兰胺酸的使用与减少手术内流血损失有关.
- 这种药物可能有助于最大限度地减少血液损失和输血需要在广泛的手术,如腹膜切除.
相关概念视频
01:22Aneurysm IV: Nursing Management
11
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
11
01:16Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
479
Intravenous regional anesthesia or the Bier block technique is used to anesthetize a specific limb or extremity. It uses exsanguinated or blood-drained vessels to transport local anesthetics or LAs to the peripheral nerve trunks. Lidocaine without vasoconstrictors like epinephrine is most commonly used for this technique. Other drugs used are prilocaine, ropivacaine, and chloroprocaine. Bupivacaine is not recommended for this technique due to its high cardiac toxicity.
One of the advantages of...
One of the advantages of...
479