在长度健康行为研究中评估符合生态瞬间评估的下降:临床试验分析
Sarah Tonkin1, Julie Gass2,3, Jennifer Wray4,5
1Stephenson Cancer Center, Tobacco Settlement Endowment Trust Health Promotion Research Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States.
Journal of medical Internet research
|June 22, 2023
概括
生态暂时评估 (EMA) 合规性在9周内略有下降,但对于跟踪健康行为仍然有效. 年轻,就业和易退学的参与者显示下降幅度更大,这表明需要有针对性的干预措施.
科学领域:
- 行为健康 行为健康
- 数字健康数字健康
- 临床试验 临床试验
背景情况:
- 生态瞬间评估 (EMA) 对于评估随时间推移的行为健康至关重要.
- 欧洲药物管理局的有效性取决于参与者持续遵守.
- 降低合规性威胁到现实世界数据收集的准确性.
研究的目的:
- 在使用香烟的成年人中,评估9周内EMA合规的时间进程.
- 在戒烟试验中确定每周遵守率的预测因素.
- 将之前的短期合规调查结果延长到更长的评估期.
主要方法:
- 在戒烟RCT中,每天吸烟的257名成年人每天在9周内每天完成智能手机EMA.
- 计算了每周的合规性,并通过多层次建模评估了随时间变化的变化.
- 分析了参与者的特征,以预测合规性和其下降.
主要成果:
- 预定早晨 (86%) 与随机 (58%) 评估的初始遵守率更高.
- 每周对EMA的遵守率线性下降 (早晨:每周2%;随机:每周1%).
- 年龄较小,全职工作和学业学预测了更大的合规性下降.
结论:
- 在延长9周的协议中,EMA的合规性呈现出适度的线性下降.
- 数据支持EMA在几个月内跟踪健康行为和治疗机制的有效性.
- 未来的研究应该专注于提高特定子组的合规性,并利用合规性下降来防止学.
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