不同的RNA病毒感染海,鱼类的主要外寄生虫
Tianyi Chang1, Brian P V Hunt1,2,3, Junya Hirai4
1Department of Earth, Ocean and Atmospheric Sciences, University of British Columbia, Vancouver, Canada.
PLoS pathogens
|June 22, 2023
概括
这项研究在海中发现了32种新的RNA病毒,扩大了对类病毒的了解,并揭示了跨王国的病毒传播. 这些发现凸显了这些重要的鱼类外寄生虫中显著的,以前未知的病毒多样性.
科学领域:
- * 病毒学 病毒学
- * * 海洋生物学 海洋生物学
- * 关节动物基因组学
背景情况:
- * 海是主要的外寄生虫,影响鱼类健康和经济.
- * 海与野生鱼数量下降有关.
- *以前对海病毒的了解仅限于两个RNA病毒群.
研究的目的:
- * 识别和描述感染关键海物种的新型病毒.
- * 研究海病毒的多样性和进化起源.
- * 确定海中发现的病毒是否在宿主体内复制.
主要方法:
- *对三种海物种的转录组数据分析:Lepeophtheirus salmonis,Caligus clemensi和Caligus rogercresseyi.
- * 病毒序列的识别和遗传学分析.
- *检测病毒衍生的小干扰RNAs (viRNAs) 和PIWI相互作用RNAs (piRNAs),以确认感染和复制.
主要成果:
- * 发现了32种以前未知的RNA病毒,代表了多种病毒类型和潜在的新家族/系.
- * 海感染和复制的证据,由viRNAs的存在表明.
- *鉴定了与植物,真菌和寄生虫带病毒相关的病毒,表明跨王国传播.
- 在C. rogercresseyi的多个生命阶段发现了病毒.
结论:
- * 这项研究显著扩大了类动物已知的病毒多样性.
- * 它证实海可以携带并复制各种RNA病毒.
- *研究结果表明,关节动物和其他真核生物之间有广泛的进化跨王国和跨族群的病毒转换.
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