短期和长时间小睡对模拟夜班工作期间血压的影响:一个随机交叉试验
P Daniel Patterson1,2, Tiffany S Okerman1,2, David G L Roach1
1School of Medicine, Department of Emergency Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Prehospital emergency care
|June 22, 2023
概括
夜班工作可以抑制血压下降. 在模拟的夜班中,较长的午睡 (2小时) 改善了血压,比较短的午睡 (30分钟) 更低,这表明午睡可以恢复健康的血压模式.
科学领域:
- 心血管生理学心血管生理学
- 睡眠医学 睡眠医学
- 职业健康 职业健康 职业健康
背景情况:
- 睡眠期间血压下降与不良的心血管结果有关.
- 众所周知,夜班工作会扰乱正常的昼夜节律,导致血压下降.
- 之前的研究表明,60分钟或更长时间的午睡可能是恢复夜班期间健康的血压下降所必需的.
研究的目的:
- 为了研究不同午睡时间 (30分钟与2小时) 在模拟夜班工作期间对血压下降的影响.
- 为了确定长时间的午睡是否比短时间的午睡更有效地恢复正常的血压下降模式.
- 为了测试一个假设,一个更长的午睡时间将产生更大的恢复BP入相比较短的午睡.
主要方法:
- 采用随机交叉实验室研究设计,参与者接受了三个72小时的条件,包括一个12小时的模拟夜班.
- 午睡条件包括30分钟的午睡,两小时的午睡和没有午睡的控制.
- 门诊血压监测每小时进行一次,在午睡期间测量更频繁,以评估血压下降模式.
主要成果:
- 虽然平均百分比的血压下降在30分钟和2小时的午睡之间没有显著差异,但更高比例的参与者在午睡2小时时内实现了10-20%的缩和扩张血压下降.
- 在30分钟的午睡期间,每增加一分钟的睡眠都与静缩血压下降的0.60%的改善和静缩血压下降的0.68%的改善有关.
- 这些发现表明,正常血压下降的相对进展与小睡期间睡眠时间的增加有关.
结论:
- 恢复正常/健康的血压下降可以通过模拟夜班期间的短时间和长时间的午睡机会来实现.
- 较长的2小时的午睡在促进血压下降方面似乎更有效,而较短的30分钟的午睡则更有效.
- 这项研究支持这样一个假设:更长的午睡时间为夜班工作期间的血压调节提供了更大的好处.
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