超加工食品摄入量和发生静脉血栓栓塞的风险:前性队列研究
Shuai Yuan1, Jie Chen2, Tian Fu3
1Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Clinical nutrition (Edinburgh, Scotland)
|June 22, 2023
概括
更高的超加工食品 (UPF) 消费与静脉血栓栓塞 (VTE) 风险中适度增加有关. 这项研究研究了在英国一大群体中,UPF摄入量和VTE发病率之间的关联.
科学领域:
- 营养流行病学 营养流行病学
- 心血管健康 心血管健康
- 公共卫生 营养 公共卫生 营养
背景情况:
- 超加工食品 (UPF) 的消费在全球范围内很普遍.
- 现有的研究将UPF与各种不良健康结果联系起来.
- 在UPF摄入量和静脉血栓栓塞 (VTE) 风险之间的关联仍未得到充分研究.
研究的目的:
- 调查超加工食品 (UPF) 摄入量与发生静脉血栓栓塞 (VTE) 的风险之间的关联.
- 量化与不同水平的UPF消费相关的VTE风险.
主要方法:
- 一项前性队列研究,使用了来自186323名参与者的英国生物库数据.
- 通过24小时的饮食回忆问卷评估UPF摄入量.
- 通过国家卫生登记册识别的事件VTE病例;用于分析的Cox比例危险回归.
主要成果:
- 在平均10.5年的随访期间,记录了4235起VTE病例.
- 与最低五分位数相比,最高五分位数的UPF摄入量 (以能量%) 显示VTE风险增加了15% (HR 1.15;95% CI 1.05-1.27) .
- 关联并没有因年龄,性别或体重指数而显著改变.
结论:
- 超加工食品的摄入量较高与静脉血栓栓塞的风险中等增加有关.
- 强调UPF的饮食模式可能有助于VTE的发展.
- 对UPF和VTE联系机制的进一步研究是有必要的.
相关概念视频
Venous Thrombosis I: Introduction
14
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
14
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
16
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
16
Venous Thrombosis III: Interprofessional Care
11
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
11
Venous Thrombosis IV: Nursing Management
15
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
15
Study Designs in Epidemiology
284
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
284
Introduction to Epidemiology
805
Epidemiology, known as the cornerstone of public health, involves studying the distribution and determinants of health-related events in defined populations and applying these insights to control health issues. This is essential for understanding how diseases spread, identifying populations at greater risk, and implementing measures to control or prevent outbreaks. Epidemiology addresses not only infectious diseases but also non-communicable conditions like cancer and cardiovascular disease,...
805


