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Updated: Jul 26, 2025

Author Spotlight: An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations
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Author Spotlight: An Integrated Workflow to Study the Promoter-Centric Spatio-Temporal Genome Architecture in Scarce Cell Populations

Published on: April 21, 2023

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通过空间细分的单细胞转录组学揭示了对细胞转录身份的积极影响

David B Morse1, Aleksandra M Michalowski2, Michele Ceribelli3

  • 1Cavendish Laboratory, Department of Physics, University of Cambridge, J J Thomson Ave, Cambridge, UK; Division of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA; John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Cell systems
|June 22, 2023
PubMed
概括

这项研究引入了外源 perfusion (SEEP) 的细分,这是一种新的方法,将细胞位置与3D疾病模型中的基因活性联系起来. SEEP有助于了解空间环境如何影响癌症中的细胞身份.

关键词:
在RNA测序过程中,RNA测序基因组学就是基因组学.瘤学 在瘤学方面.卵巢癌是发生在卵巢的癌症.这就是scRNA-seqq.单细胞转录组学 单细胞转录组学空间转录学 空间转录学空间分辨率的转录学

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