患者和医生报告的疾病活动之间的不一致性在成人异常发炎性肌肉病变中
Shiri Keret1, Didem Saygin2, Siamak Moghadam-Kia2
1Rheumatology Unit, Faculty of Medicine, Bnai-Zion Medical Center, Technion, Haifa, Israel.
患有异常性炎症性肌肉病变 (IIM) 的患者评估最受疲劳,疼痛和身体功能的影响. 了解这些患者报告的因素是改善护理和解决与医生评估差异的关键.
科学领域:
- 类风湿病学 类风湿病学
- 临床医学 临床医学
- 患者报告的结果
背景情况:
- 患者报告的全球疾病活动 (患者-全球) 是肌肉炎评估的关键措施.
- 患者和医生的全球疾病活动评估之间的差异可能会阻碍共享决策.
- 确定患者全球的驱动因素对于在异常发炎性肌肉病 (IIM) 中全面评估患者至关重要.
研究的目的:
- 调查影响IIM患者患者报告的全球疾病活动 (患者-全球) 的因素.
- 分析患者-全球和医生报告的全球疾病活动 (医生-全球) 之间的差异.
- 了解各种临床和患者报告的措施对IIM患者全球的贡献.
主要方法:
- 一项前性观察横截面研究招募了患有IIM的成年人.
- 收集的数据包括患者-全球,医生-全球,疾病活性测量,功能评估 (例如手动肌肉测试,HAQ,身体功能) 和生物标志物 (例如肌酸酶).
- 线性回归分析了患者-全球的决定因素;不一致性被定义为患者-全球和医生-全球之间的≥3点差异.
主要成果:
- 身体功能和疲劳是患者全球最强的贡献者,其次是疼痛,体力活动和生活质量.
- 医生-全球主要是由肌肉疾病活动驱动的.
- 30%的患者表现出患者-全球和医生-全球之间的不一致性,在66%的病例中,患者报告了较高的疾病活性.
结论:
- 疲劳,疼痛和体力活动显著推动了IIM患者和医生之间疾病活动感知的差异.
- 解决患者和医生的观点之间的差距对于提供以患者为中心的护理至关重要.
- 认识到患者报告的症状的影响,可以导致 IIM 的更有效的管理策略.
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