相关实验视频
Updated: Jul 26, 2025

08:28
Stereolithographic 3D Printing with Renewable Acrylates
Published on: September 12, 2018
9.5K
新型抗水解耐药抗菌单体用于牙科树脂粘合剂
Piangkwan Saiprasert1, Chittreeya Tansakul2, Arthit Pikulngam2
1Department of Prosthetic Dentistry, Faculty of Dentistry, Prince of Songkla University, Songkhla, Thailand, 90112.
Journal of dentistry
|June 22, 2023
概括
基于甲基胺的新型四级化合物 (QAC) 单体表现出强大的抗菌活性,并增强树脂粘合性能. 这些QAC单体为牙科应用提供了改进的物理和机械特性.
科学领域:
- 牙科材料科学 牙科材料科学
- 聚合物化学 聚合物化学
- 抗菌剂 抗菌剂 抗菌剂
背景情况:
- 牙树脂粘合剂容易受到细菌殖民和降解.
- 开发耐水解抗菌单体对于改善牙科修复材料至关重要.
研究的目的:
- 合成和表征基于甲烯胺的新型四级化合物 (QAC) 单体.
- 评估这些单体的抗菌疗效和细胞毒性.
- 评估将这些单体纳入树脂粘合剂对其物理,机械和粘合性能的影响.
主要方法:
- 基于甲基胺的QAC单体 (MAUPB,MADPB) 和甲基酸衍生物 (MUPB,MDPB) 的合成和表征.
- 对口腔细菌的最小抑制 (MIC) 和杀菌 (MBC) 度的确定.
- 评估单体细胞毒性和树脂转化度 (DC%).
- 评估实验性树脂粘合剂的细菌附着,屈曲强度和剪接强度.
主要成果:
- 抗菌活性顺序:MDPB≥MUPB>MADPB>MAUPB;细胞毒性顺序:MAUPB>MADPB>MUPB>MDPB.
- 加入MAUPB在BisGMA/HEMA树脂中增加了DC%,在BisGMA/TEGDMA和BisGMA/HEMA树脂中减少了细菌的附着.
- 与MUPB和对照树脂相比,MAUPB的树脂在储存3个月后表现出优越的屈曲强度和显著更高的树脂-丁丁剪接强度.
结论:
- 基于甲基胺的QAC单体MAUPB在树脂粘合剂中表现出显著的抗菌特性和优越的物理/机械性能,与其甲基酸盐对应物MUPB相比.
- 这些新型单体有望为制造先进的,抗菌的和耐水解的牙树脂粘合剂提供增强的粘合强度.
相关概念视频
Anionic Chain-Growth Polymerization: Overview
2.1K
The polymerization process that involves carbanion as an intermediate is called anionic polymerization. It is also a type of addition or chain-growth polymerization. Anionic polymerization gets initiated by a strong nucleophile such as an organolithium or a Grignard reagent. The most commonly used initiator for anionic polymerization is butyl lithium. Monomers involved in anionic polymerization must possess a vinyl group bonded to one or two electron-withdrawing groups. For instance,...
2.1K
Waterproofing and Anti-Bacterial Admixtures in Concrete
103
Concrete's susceptibility to water absorption is due to the capillary action within the pores of its hydrated cement paste. This action draws water in, creating the need for waterproofing admixtures to prevent such penetration. The efficacy of these admixtures is contingent upon the water pressure, with variations arising from different conditions such as rain, capillary rise, or hydrostatic pressure in structures intended to hold water.
Waterproofing admixtures render concrete hydrophobic,...
Waterproofing admixtures render concrete hydrophobic,...
103
Hydrolysis
106.3K
Overview
Hydrolysis is a chemical reaction in which the addition of water breaks down a polymer into its simpler monomer units. For example, peptides break into amino acids, carbohydrates into simple sugars, and DNA into nucleotides. Enzymes often facilitate these processes.
Hydrolysis Reverses Dehydration Synthesis
Complex carbohydrates can be broken down by breaking the bonds between individual sugar units. The reaction breaks a glycosidic bond as water is added to the compound. The...
Hydrolysis is a chemical reaction in which the addition of water breaks down a polymer into its simpler monomer units. For example, peptides break into amino acids, carbohydrates into simple sugars, and DNA into nucleotides. Enzymes often facilitate these processes.
Hydrolysis Reverses Dehydration Synthesis
Complex carbohydrates can be broken down by breaking the bonds between individual sugar units. The reaction breaks a glycosidic bond as water is added to the compound. The...
106.3K
Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)
2.0K
Acyclic diene metathesis polymerization or ADMET polymerization involves cross-metathesis of terminal dienes, such as 1,8-nonadiene, to give linear unsaturated polymer and ethylene. As ADMET is a reversible process, the formed ethylene gas must be removed from the reaction mixture to complete the polymerization process.
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...
Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...
2.0K
Chemical Agents for Microbial Control
141
Chemicals play important roles in controlling microbial growth by targeting microbial structures and functions as sanitizers, antiseptics, disinfectants, and sterilants.Alcohols are commonly used sanitizers, effectively disrupting lipid membranes, which compromises cell integrity. They are also used as antiseptics and disinfectants due to their rapid action and versatility.Phenols and their derivatives phenolics , known for denaturing proteins and disrupting cell membranes, are particularly...
141

