病和结核病:一个系统的审查和元分析
P Jamshidi1,2, B Danaei1, M Arbabi1
1Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Pulmonology
|June 22, 2023
概括
暴露于粉尘的工人,包括矿工,面临患结核病的风险增加. 对于这些人来说,建议对病和结核病进行常规查.
科学领域:
- 职业健康 职业健康 职业健康
- 呼吸系统医学 呼吸系统医学
- 传染性疾病 传染性疾病
背景情况:
- ,一个由暴露于粉造成的肺部疾病,与其他严重的健康问题有关.
- 结核病是病和结核病的联合感染.
- 了解病患者肺结核风险对于公共卫生至关重要.
研究的目的:
- 系统地审查和对有病患者肺结核风险进行元分析.
- 评估粉暴露和结核病感染之间的关联.
主要方法:
- 在PubMed/Medline和Embase数据库进行系统搜索,截至2022年9月.
- 包括对病患者结核病的队列和病例控制研究.
- 使用随机效应模型来计算聚合风险比率和95%置信区间的元分析.
主要成果:
- 七项研究符合审查条件,其中4项被纳入了元分析 (共5884名参与者).
- 分析显示,综合风险比为1.35 (95% CI为1.18-1.53),表明结核病风险增加.
- 观察到显著的异质性 (I2: 94.30%).
结论:
- 病和粉暴露显著增加了结核病的风险.
- 对于矿工等高风险人群,建议对病和结核病进行常规查.
- 早期检测和干预对于管理共同感染至关重要.
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