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Updated: Jul 26, 2025

Strategic Screening and Characterization of the Visual GPCR-mini-G Protein Signaling Complex for Successful Crystallization
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Strategic Screening and Characterization of the Visual GPCR-mini-G Protein Signaling Complex for Successful Crystallization

Published on: March 16, 2020

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一个基于卷轴-卷轴的设计策略,用于G蛋白结合受体的热稳定

Marwa Amer1, Oneda Leka1, Piotr Jasko1

  • 1Laboratory of Biomolecular Research, Division of Biology and Chemistry, Paul Scherrer Institute, 5232, Villigen PSI, Switzerland.

Scientific reports
|June 22, 2023
PubMed
概括

研究人员设计了稳定的G蛋白合受体 (GPCRs),使用线圈-线圈域来改善结晶和结构确定. 这种新的方法提高了GPCR的稳定性和可溶性,用于结构研究.

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