在前体障碍患者与健康对照者之间,认知,功能和双重任务步态之间的相互作用
Marousa Pavlou1,2, Sergi G Costafreda3, William Galsworthy4
1Centre for Human and Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences and Medicine, King's College London, Shepherd's House, Guy's Campus, London, SE1 1UL, UK. marousa.pavlou@kcl.ac.uk.
Scientific reports
|June 22, 2023
概括
带有前庭功能障碍 (PwVD) 的人表现出认知功能和步行表现受损,特别是在双重任务测试期间. 将认知评估与步态测试相结合,可以改善PwVD的干预措施.
科学领域:
- 神经科学是一个神经科学.
- 康复科学 康复科学 康复科学
- 人类运动科学科学 人类运动科学
背景情况:
- 静脉功能与认知能力密切相关,影响日常生活活动.
- 双任务 (DT) 测试评估认知运动需求与前庭功能障碍 (PwVD),功能步行和跌倒风险相关的人.
- 了解前体缺陷,认知负载和步态之间的相互作用对于有效的康复至关重要.
研究的目的:
- 在PwVD中开发DT条件下的功能步态的预测模型.
- 澄清前庭功能障碍,个体特征和任务类型对步行表现的影响.
- 为了确定运动和认知需求对PwVD功能步态的影响.
主要方法:
- 一项病例控制观察研究,涉及39名PwVD和62名健康对照.
- 功能性步行评估 (FGA) 在单任务和DT条件下进行 (运动,算术,识字任务).
- 多重线性回归和双任务成本 (DTC) 用于分析步行表现和DT干扰.
主要成果:
- 与对照组相比,PwVD在所有条件下表现较差 (p < 0.001).
- 在PwVD中,运动 (-3.94%) 和算术 (-22.77%) 任务的DTC显著更高,空间工作记忆受损.
- 在单个和DT条件下FGA的预测模型解释了PwVD的实质性差异 (66-76%),注意力,视觉记忆和性别是关键贡献者.
结论:
- 在PwVD中,认知能力明显受损,影响功能性步行.
- 运动,算术和识字任务显著干扰PwVD的功能步行表现.
- 将认知评估和FGA与认知组件整合到协议中可以增强PwVD的干预措施.
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