在试验后获得和使用暴露前预防在南非德班,南非
Ivana Beesham1, Cecilia Milford1, Jenni Smit1
1Wits MatCH Research Unit (WMRU), Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of the Witwatersrand, Durban, South Africa.
BMC public health
|June 22, 2023
概括
由于设施障碍,南非妇女在试验后获得口服暴露前预防 (PrEP) 的机会有限. 改善对这种艾滋病毒预防方法的获取对于持续使用至关重要.
科学领域:
- 公共卫生 公共卫生
- 预防艾滋病毒 预防艾滋病毒
- 临床试验 临床试验
背景情况:
- 艾滋病毒临床试验越来越多地使用口服暴露前预防 (PrEP) 作为标准预防方法.
- 有限的数据存在于试验后的访问和继续使用PrEP的参与者谁愿意这样做.
研究的目的:
- 探索在南非德班妇女中对试验后PrEP获取和持续使用的障碍和促进因素.
- 在临床试验后确定改善PrEP持续使用的策略.
主要方法:
- 与13名参与ECHO试验并选择在试验后继续使用PrEP的女性进行了半结构化深度采访.
- 面试的重点是试验结束后获得和使用PrEP的经验.
- 利用NVivo提供的专题分析来解释数据.
主要成果:
- 在13名女性中,只有6名女性在试验后获得了PrEP,其中5名随后停止了治疗.
- 关键障碍包括长队,不方便的时间,遥远的设施和运输成本.
- 一些妇女在当地诊所面临PrEP的不可用性,尽管想要使用它.
结论:
- 显著的障碍阻碍了试验后的PrEP获取和持续使用.
- 需要采取策略,比如减少等待时间,改善运营时间和更广泛的可用性.
- 在南非扩大口服PrEP接入可能会改善未来的试验后利用.
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