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Updated: Jul 26, 2025

Tandem Affinity Purification of Protein Complexes from Eukaryotic Cells
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发现CDK9-环素T1复合物的基于HyT的降解剂

Rongkun Lin1, Jie Yang2, Ting Liu1

  • 1School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China.

Chemistry & biodiversity
|June 22, 2023
PubMed
概括

科学家们开发了一种基于水标签 (HyT) 的新型降解剂LL-CDK9-12,以准CDK9-环素T1复合体. 这种新分子有效降解复合物,并显示出前列腺癌治疗的前景.

关键词:
在CDK9中,CDK9是CDK9.环林 T1 T1 的时间.降解剂降解剂是一种降解剂.疏水标签是指疏水的标签蛋白质降解 蛋白质降解

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