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相关概念视频

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Changes in Skin Color: Clinical Perspectives01:14

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
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Pigmentation01:19

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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
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肌肤色素过高指数在黑色素瘤:一种对经典评分系统的补充方法.

Kristine Heidemeyer1, Simone Cazzaniga1,2, Laurence Feldmeyer1

  • 1Department of Dermatology, Inselspital University Hospital of Bern, University of Bern, Bern, Switzerland.

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概括

新的皮肤超颜色指数 (SHI) 准确地测量了黑色素瘤的严重程度,并且在医生中显示出比现有得分更好的可靠性. 该指数提供了一个精确,具有成本效益的工具,用于跟踪疹治疗进展.

关键词:
梅拉斯玛是一种神经性疾病.球队的成绩 球队的成绩 球队的成绩皮肤色素过高指数指数

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科学领域:

  • 皮肤病学 皮肤病学
  • 医疗成像医学成像
  • 临床评估 临床评估

背景情况:

  • 梅拉斯马是一种复发性皮肤疾病,严重影响生活质量.
  • 客观测量得分对于精确的患者随访和治疗响应评估在瘤中是必要的.

研究的目的:

  • 为了验证皮肤超颜色指数 (SHI) 与已建立的黑色素评分系统相比.
  • 为了证明SHI的优越级别之间的可靠性.
  • 开发SHI映射,用于整合到常见的质瘤得分.

主要方法:

  • 五位皮肤科医生计算了SHI和标准乳腺瘤得分.
  • 评估者之间的可靠性是使用类内相关系数 (ICC) 来评估的.
  • 用肯德尔相关系数评估一致性.

主要成果:

  • SHI与MASI-darkness (0.48),MSI-pigmentation (0.45) 和MSS (0.6) 显示出强烈的一致性.
  • 使用步骤函数映射SHI,改善了MASI-darkness (ICC差异0.22) 和MSI-pigmentation (ICC差异0.19) 的评分器间可靠性.
  • 这种映射导致了优秀的协议.

结论:

  • 皮肤超颜色指数 (SHI) 是一种有价值,时间和成本高效的工具,用于监测黑色素患者.
  • SHI显示了与既定分数和优越的评级者间可靠性的强烈一致.
  • 它适用于临床研究和常规实践,用于评估瘤疗法.