疫苗接种与SARS-CoV-2病例之间的关系,项目突破病例,以及巴西巴拉纳州杜斯维辛霍斯的死亡
Marina Wust Vasconcelos1,2, Flavia Regina Oliveira de Barros2,3,4, Jéssica Cousseau Pilonetto1,2
1Programa de Pós-Graduação em Biotecnologia-PPGBIOTEC, Universidade Tecnológica Federal do Paraná, Dois Vizinhos, Paraná, Brazil.
Journal of medical virology
|June 23, 2023
概括
在巴西的一座城市,COVID-19疫苗接种显著减少了病例和死亡. 即使在Omicron变种中,接种疫苗也保持了较低的死亡率,证明了疫苗的有效性.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 疫苗学 疫苗学 疫苗学
背景情况:
- 由于COVID-19的流行,需要快速开发和部署疫苗.
- 在现实环境中评估疫苗的有效性对于公共卫生战略至关重要.
研究的目的:
- 评估COVID-19疫苗接种对巴西一个人口密度低的城市感染和死亡率的影响.
- 为了确定疫苗接种覆盖率的重要疾病控制的门.
主要方法:
- 一年时间 (2021年1月至2022年1月) 的COVID-19病例和死亡数据集的回顾性分析.
- 疫苗接种覆盖率与发病率和死亡率的相关性.
- 对所使用的疫苗类型的分析.
主要成果:
- 随着疫苗接种覆盖率的增加,观察到COVID-19病例和死亡人数的减少,特别是在达到35.21%的人口覆盖率后.
- 接种了不同类型的疫苗,包括ChAdOx1-S,非活化的SARS-CoV-2 (CZ02),Tozinameran和Ad26.COV2-S.
- 尽管随后发生了Omicron变种的爆发,但死亡率仍然很低 (每1000名居民0.07) 即使发病率很高 (每1000名居民68.41).
结论:
- COVID-19疫苗接种在控制感染和死亡率方面表现出显著的有效性.
- 在这个城市模型中,大约35.21%的人口接种疫苗的覆盖率值与疾病控制有关.
- 接种疫苗可以防止严重的后果,包括在Omicron变种激增期间.
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