相关实验视频
Updated: Jul 26, 2025
10:02
Use of Rabbit Eyes in Pharmacokinetic Studies of Intraocular Drugs
Published on: July 23, 2016
32.3K
一例复发的急性排泄性多形形黄斑病例成功地用静脉内Ozurdex注射治疗
Vaishali Lodhia1, Anthony G Robson2,3, Shaheeni Khoda2
1Sussex Eye Hospital, Brighton, UK.
European journal of ophthalmology
|June 23, 2023
概括
复发性急性排泄性多形形黄斑病变 (AEPVM) 已成功用内德克萨米他植入物 (Ozurdex®) 治疗. 这个病例显示了视网膜色素上皮质 (RPE) 功能的恢复和在延迟复发后的良好视觉结果.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 斑点退化症 斑点退化症
背景情况:
- 急性排泄性多形形黄斑病变 (AEPVM) 是一种罕见的疾病.
- AEPVM的复发不常见,特别是在9年间隔后.
- 这一案例突出了AEPVM晚期复发与显著的视力损伤.
研究的目的:
- 报告一次性复发的 AEPVM.的独特案例.
- 调查复发性AEPVM的静脉内皮质类固醇治疗的疗效.
- 为了记录治疗后视网膜功能和视觉敏度的恢复.
主要方法:
- 一名45岁的女性患者被诊断患有复发性AEPVM.
- 诊断工具包括 fundus 检查,光学连贯性断层扫描 (OCT) 和电生理学 (电眼镜).
- 治疗最初涉及口服类固醇,随后是持续释放的内植入物 (Ozurdex®).
主要成果:
- 复发性AEPVM呈现双边囊性黄斑胀 (CMO) 和视力敏度降低.
- 电生理学证实了严重的一般化视网膜色素表皮 (RPE) 功能障碍.
- 用Ozurdex®治疗导致CMO完全消失,视力敏度改善,持续恢复.
结论:
- 在经过相当长的无病期后,AEPVM的复发可能会发生.
- 静脉内甲松植入物 (Ozurdex®) 是一种有效的治疗方法,用于治疗CMO复发性AEPVM.
- 成功治疗可以恢复RPE功能和良好的视觉结果.
相关概念视频
01:27Open Angle Glaucoma: Treatment
481
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
481
01:28Angle Closure Glaucoma: Treatment
577
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
577