通过生物催化聚环化,合成 (+) - 异甲, (+) - -16-one 和 3-deoxychavalone A 的化学酶合成

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Wen Xiao1, Su-Jing Wang1, Ming-Zhu Yu1

  • 1State Key Laboratory of Chemical Oncogenomics, Guangdong Provincial Key Laboratory of Chemical Genomics, AI for Science (AI4S) Preferred Program, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen 518055, China. zxiang@pku.edu.cn.

Organic & biomolecular chemistry
|June 23, 2023
PubMed
概括

斯卡 - 霍环酶 (SHC) 有效地催化基拉尼尔基拉尼的立体选择性循环. 这使得复杂的 terpenoids,如海绵型 diterpenoids 和 meroterpenoid 3-deoxychavalone A. 的简洁合成成为可能.

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