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在不同阶段的尿道内支架和常规支架的比较:一个系统的综述与元分析
Chao Zheng1, Jixue Wang2, Tengteng Jian2
1Department of Neurology and Neuroscience Center, The First Hospital of Jilin University, Changchun, China.
Minerva urology and nephrology
|June 23, 2023
概括
输尿管内支架在减少支架相关症状 (SRS) 和改善患者的治疗结果方面表现有前途,特别是在治疗的中后阶段. 对于这种创新的尿道支架方法,需要进行进一步的临床研究.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 医疗器械 医疗器械
- 手术创新 在外科创新.
背景情况:
- 支架相关症状 (SRS) 是尿道支架的常见不良影响.
- 目前正在开发肠道支架,以潜在地缓解SRS并改善与膀相关的问题.
- 关于尿道内支架的临床疗效和安全性的证据仍然有限.
研究的目的:
- 系统地审查和元分析尿道内支架的疗效和安全性.
- 为了比较尿管内支架与常规尿管支架的结果.
主要方法:
- 随机临床试验 (RCT) 的系统审查和元分析.
- 在2023年2月之前搜索了PubMed,科学网,Medline,Embase和Cochrane图书馆.
- 包括对尿道内支架,尿道透视,尿路结石,SRS和下尿路症状的研究.
主要成果:
- 其中包括六个RCT.
- 尿管内支架在中期显著改善了尿路症状,疼痛评分和一般健康状况.
- 在尿路症状指数,VAS得分,生活质量,一般健康和疼痛得分方面,在晚期观察到更好的结果.
- 在早期阶段或长期评估中没有发现显著差异.
结论:
- 输尿管内支架的疗效和安全性与常规支架相比或更高,特别是在术后7-14天的常见期内.
- 这些发现支持进一步的临床研究和尿道内支架的应用.
- 这种方法有可能改善尿路支架后的患者舒适度和结果.
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