在过去的20年中,对中风和肠道微生物群之间的相关性进行了一项研究:一项文献计量分析
Shengnan Han1, Longhui Cai2, Peipei Chen3
1Clinical Medical College of Acupuncture, Moxibustion and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, China.
Frontiers in microbiology
|June 23, 2023
概括
这项研究分析了关于中风和肠道微生物群的660篇论文,揭示了脑肠轴和炎症等关键研究领域. 未来的研究很可能会集中在机制和心血管联系上.
科学领域:
- 神经科学是一个神经科学.
- 微生物学 微生物学
- 心血管科学 心血管科学
背景情况:
- 肠道微生物群在各种生理和病理过程中起着至关重要的作用.
- 新出现的证据表明,肠道微生物群失生症与中风的发生和发展之间存在重要联系.
- 了解这种复杂的关系对于开发新的治疗策略至关重要.
研究的目的:
- 提供关于中风和肠道微生物群领域的知识结构,研究热点和未来趋势的全面概述.
- 分析过去二十年中关于中风和肠道微生物群之间的关系研究的演变.
主要方法:
- 对2002年至2021年间发表的660篇论文进行了科学度分析.
- 数据是从科学网络核心集合中获取的.
- 使用CiteSpace V软件进行可视化和分析.
主要成果:
- 美国,英国和德国是领先的研究中心. 关键机构包括克利夫兰诊所,南方医学大学和中国科学院.
- "自然"杂志,斯坦利·勒·哈森 (Stanley L. Hazen) 和唐·惠 (Tang WHW) 在出版物和引文中占据了重要地位.
- 同时发生的分析确定了诸如大脑-肠道微生物群轴,便微生物组移植和TMAO等集群. 关键词爆炸包括"肠道微生物群"",缺血性中风"",炎症"和"心血管疾病".
结论:
- 预计关于中风和肠道微生物群的年度出版物数量将大幅增加.
- 未来的研究很可能会关注潜在的机制,包括炎症,免疫路径,TMAO和便移植.
- 研究这些机制与特定的心血管疾病之间的联系是未来潜在的研究方向.
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