怀孕期间的胎儿与母亲的相互作用:一个"三合一"的视角
Yonghong Zhang1, Zhaozhao Liu2, Haixiang Sun1
1Center for Reproductive Medicine and Obstetrics and Gynecology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.
Frontiers in immunology
|June 23, 2023
概括
人类成功怀孕取决于母亲对胎儿的免疫耐受性. 本综述探讨了免疫细胞和微生物群在母胎界面的相互作用,这对妊娠健康和并发症至关重要.
科学领域:
- 生殖免疫学 生殖免疫学
- 母胎界面生物学 母胎界面生物学
- 微生物组研究 微生物组研究
背景情况:
- 母亲的免疫耐受性对于成功怀孕至关重要.
- 母胎界面涉及复杂的细胞相互作用.
- 子宫微生物群可能会影响怀孕的结果.
研究的目的:
- 审查当前有关热囊细胞与免疫细胞相互作用的知识.
- 要突出孕期母亲与胎儿界面的作用.
- 讨论微生物群对妊娠进展的影响.
主要方法:
- 最近研究的文献综述.
- 对母胎界面的细胞相互作用进行分析.
- 免疫细胞和微生物群的角色的表征.
主要成果:
- 热细胞和状免疫细胞的交叉交互对于孕产妇对胎儿的耐受性至关重要.
- 结合性细菌有助于维持怀孕.
- 功能障碍相互作用与妊娠并发症有关.
结论:
- 了解孕产妇与胎儿之间的相互作用是管理妊娠并发症的关键.
- 未来的研究应该专注于治疗应用.
- 免疫耐受性和微生物群对于健康的怀孕至关重要.
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