通过心脏代谢指标预测中国中年和老年人的抑郁症状:基于人口的横截面研究
Ying Wang1, Xiaoyun Zhang1, Yuqing Li1
1Department of Graduate School, Wannan Medical College, Wuhu, An Hui, China.
Frontiers in psychiatry
|June 23, 2023
概括
心脏代谢指标在中老年和老年人中预测抑郁症状的可能性很低. 虽然一些指标显示出轻微的关联,但其他指标是无效的,强调需要进一步研究有效的预测措施.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 心血管健康 心血管健康
背景情况:
- 抑郁症状是一种严重的精神疾病,在老年人中患病率越来越高,构成了公共卫生挑战.
- 了解中年和老年人抑郁症状的预测因素对于早期识别和干预至关重要.
研究的目的:
- 研究中老年和老年中国成年人抑郁症状的各种心脏代谢指标的预测价值.
- 确定有效的人类指数,以便在这个人口群体中早期检测抑郁症状.
主要方法:
- 采用了2011年中国健康与退休长度研究 (CHARLS2011) 的数据,其中有8942名45岁及以上的参与者.
- 评估了13个心脏代谢指标,包括BMI,腰围,WHtR,LAP,BRI,CVAI,TyG-BMI和TyG-腰围.
- 采用二进制物流回归和ROC曲线分析来评估预测准确性和最佳截止值.
主要成果:
- 一些心脏代谢指标,包括BMI,腰围,WHtR,LAP,BRI,CVAI,TyG-BMI和TyG-腰围,显示男性抑郁症状的预测能力较弱 (AUC<0.5).
- 在女性中,BMI,LAP,TyG-BMI和TyG腰围也显示出抑郁症状的预测能力较弱 (AUC<0.5).
- 内脏脂肪指数 (VAI),身体形状指数 (ABSI),状指数和甘油三糖指数 (TyG指数) 在两种性别中都没有预测抑郁症状.
结论:
- 大多数评估的心脏代谢指标在预测中年和老年人中抑郁症状的价值有限.
- 这些发现表明需要进一步研究,以确定更强大的预测因子,以便在这个人群中早期检测抑郁症状.
- 改进的早期识别策略对于减少抑郁症状的流行率和改善健康结果至关重要.
相关概念视频
Psychoneuroimmunology: Cardiovascular Disease
54
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
54
Coronary Artery Disease I: Introduction
28
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
28
Stress and Mental Health
186
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
186
Depressive Disorders: Etiology
141
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
141


