偏头痛在炎症性肠病中的流行,系统性审查和元分析
Hamide Olfati1, Omid Mirmosayyeb2,3,4, Ali Mahdi Hosseinabadi3
1Department of Endocrinology, Razi hospital, Qazvin, Iran.
偏头痛影响19%的炎症性肠病 (IBD) 患者. 本系统性审查和元分析综合了关于IBD中偏头痛患病率的当前数据,包括性结肠炎和克罗恩病.
科学领域:
- 胃肠病学和神经病学
- 流行病学 流行病学
- 伴发病性研究研究
背景情况:
- 炎症性肠病 (IBD) 与许多并发症有关,包括偏头痛.
- 之前的研究报告IBD患者的偏头痛发病率不同.
- 清楚地了解IBD中偏头痛的患病率对于患者护理至关重要.
研究的目的:
- 进行系统审查和元分析.
- 估计IBD诊断的患者中偏头痛的综合患病率.
- 分析特定IBD亚型中的偏头痛患病率:性结肠炎 (UC) 和克罗恩病 (CD).
主要方法:
- 在主要数据库 (PubMed,Scopus,EMBASE,Web of Science,Google Scholar) 进行全面的文献搜索,截至2021年5月.
- 包括报告IBD患者偏头痛患病率的横截面研究.
- 由两位研究人员进行的独立审查和对10项涉及62,554名患者的研究进行的分析.
主要成果:
- 在IBD患者中,偏头痛的整体综合患病率为19% (95%CI:15-22%).
- 偏头痛的患病率在性结肠炎中为10%,在克罗恩病中为24% (95% CI: 17-30%).
- 在IBD病例中,患上偏头痛的几率显著增加 (OR=1.51,95%CI:1-2.27).
结论:
- 偏头痛是炎症性肠道疾病患者的重要并发症.
- 在IBD患者中,偏头痛的综合患病率为19%,克罗恩病的患病率高于性结肠炎.
- 这些发现强调了在IBD患者群体中查和管理偏头痛的重要性.
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