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Updated: Jul 25, 2025

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

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促进体中的高阶G四复合体是尚未开发的药物标

Robert C Monsen1

  • 1Department of Medical Oncology and Hematology, UofL Health Brown Cancer Center, University of Louisville, Louisville, KY, United States.

Frontiers in chemistry
|June 23, 2023
PubMed
概括

高级G四复合体 (G4s) 提供比单体形式更有选择性的癌症药物标. 专注于这些复杂结构可以克服难以向蛋白质G4连接体开发的局限性.

关键词:
它们是DNA DNA DNA DNA.在G-四重复 (G4) 中.药物目标是药物目标.更高层次的 G4 的 G4.活动主办人 活动主办人

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