在EACVI-AFib回声注册表中的标准和高级回声心脏学参数的中心间可重现性
Ciro Santoro1, Erwan Donal2, Julien Magne3
1Department of Advanced Biomedical Sciences, Federico II University Hospital, Naples, Italy.
Echocardiography (Mount Kisco, N.Y.)
|June 23, 2023
概括
心声回声学测量的可复制性,包括全球纵向应变 (GLS) 和顶峰心房纵向应变 (PALS),在实验室中进行了评估. 即使在心房动患者中,GLS和PALS也表现出优异的可重复性,这支持了它们更广泛的临床应用.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 声心图对于评估心脏功能至关重要.
- 心声回声学测量的中心间变异性可能会影响临床试验和注册数据.
- 在之前的研究中,标准心声回声学参数已经显示出低于最佳的可重现性.
研究的目的:
- 评估关键心声图测量的中心间可重复性.
- 为了比较标准回声多普勒参数的可重现性,使用先进的技术,如全球纵向应变 (GLS) 和顶峰心房纵向应变 (PALS).
- 在患有鼻节律 (SR) 和持续性心房动 (AF) 的患者中评估可再生性.
主要方法:
- 16个心声回声实验室参与了EACVI-Afib Echo Europe研究.
- 标准回声多普勒参数,GLS和PALS在10名SR和10名AF患者的存储回声检查上进行了测量.
- 为了评估测量可重复性,计算了类间相关系数 (ICC).
主要成果:
- 标准参数,如左心室质量和射出分数,显示出低于最佳的ICC.
- 减速时间表现出较差的可重现性,特别是在AF患者中 (ICC=.50).
- GLS显示出高可重现性 (SR中的ICC=.81,AF中的ICC=.78). PALS显示出适当的可重现性,基于心声回声图的变化.
结论:
- 在注册表中应谨慎使用标准回声心脏学变量,因为其可再生性不够理想.
- GLS和PALS提供优越的复制性,即使在心房的患者中也是如此.
- 建议在临床实践和研究中更广泛地采用GLS和PALS.
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