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Updated: Jul 25, 2025

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test OGTT and Insulin Tolerance Test ITT
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每日口服GLP-1受体激动剂或forglipron对于肥胖的成年人

Sean Wharton1, Thomas Blevins1, Lisa Connery1

  • 1From McMaster University, York University, and Wharton Weight Management Clinic - all in Toronto (S.W.); Texas Diabetes and Endocrinology, Austin (T.B.), and Velocity Clinical Research at Medical City, Dallas (J.R.) - both in Texas; Alliance for Multispecialty Research, Norman, OK (L.C.); and Eli Lilly, Indianapolis (S.R., R.L., X.M., K.J.M., A.H., D.R., E.P., C.K., M.K.).

The New England journal of medicine
|June 23, 2023
PubMed
概括

口服orforglipron,一种非类GLP-1受体激动剂,在肥胖的成年人中显著降低体重. 胃肠道事件是最常见的副作用,类似于注射GLP-1激动剂.

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