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Updated: Jul 25, 2025

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Dna2可以去除中性重组相关的DNA合成产生的有毒ssDNA-RPA细丝

Binyuan Zhai1, Shuxian Zhang2, Bo Li3

  • 1Center for Cell Structure and Function, Shandong Provincial Key Laboratory of Animal Resistance Biology, College of Life Sciences, Shandong Normal University, Jinan, Shandong 250014, China.

Nucleic acids research
|June 23, 2023
PubMed
概括

弥生需要Dna2去除在双链断裂 (DSB) 修复过程中产生的单链DNA (ssDNA). 耗尽Dna2会导致RPA积累,缺陷的DSB修复,以及酵母中的不活性的子.

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