性结肠炎症状严重程度和直肠切除术与多维患者报告结果的关联:一个横截面研究
Katsuyoshi Matsuoka1, Hajime Yamazaki2, Masakazu Nagahori3
1Division of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University Sakura Medical Center, 564-1 Shimoshizu, Sakura, Chiba, 285-8741, Japan. matsuoka@fk2.so-net.ne.jp.
Journal of gastroenterology
|June 23, 2023
概括
即使是轻微的性结肠炎症状也会显著降低生活质量,情绪和工作生产力. 管理活跃疾病可以改善所有患者的治疗结果.
科学领域:
- 胃肠病学 胃肠病学
- 患者报告的研究结果研究结果
- 临床流行病学 临床流行病学
背景情况:
- 您和性结肠炎:注册和社交网络 (YOURS) 是日本的一个大型,多中心,以患者为中心的注册.
- 它调查了生活方式,心理因素和临床实践模式,影响了患者报告的性结肠炎 (UC) 结果.
研究的目的:
- 探索症状严重程度和直肠切除术对UC患者患者患者报告结果的影响.
- 评估对生活质量,疲劳,焦虑/抑郁,工作生产力和睡眠的影响.
主要方法:
- 1971年,来自第三级医疗机构的UC患者被纳入了YOURS注册表.
- 经过验证的问卷评估了生活方式,心理社会因素和疾病症状 (缓解,轻度,中度,严重).
- 标准化平均差异与基于症状严重程度或直肠切除术状态的患者报告的结果得分进行了比较.
主要成果:
- 在增加症状严重程度和恶化生活质量,疲劳,焦虑,抑郁和工作生产力之间观察到线性关系.
- 患有轻度UC症状的患者报告的结果比缓解期患者更差.
- 与缓解期患者相比,接受直肠切除术的患者也报告了更糟糕的结果.
结论:
- 性结肠炎与情绪,生活质量,疲劳和工作生产力下降有关,即使在轻微的情况下也是如此.
- 活跃性性结肠炎的管理可能会改善患者报告的结果,无论疾病的整体严重程度如何.
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