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由Leishmania Tropica引起的内脏莱什曼病

Ahmet Özbilgin¹, Varol Tunalı^2,3, İbrahim Çavuş¹

¹Department of Parasitology, Faculty of Medicine, Manisa Celal Bayar University, Manisa, Turkey.

Acta parasitologica

|June 23, 2023

概括

土耳其的内脏莱什曼病 (VL) 越来越多地是由Leishmania tropica引起的,这种病原体以前与皮肤莱什曼病有关. 这种转变构成了严重的公共卫生威胁,需要进一步研究传播和适应机制.

科学领域:

寄生虫学的寄生虫学
传染性疾病传染性疾病
流行病学流行病学

背景情况:

土耳其的内脏莱什曼病 (VL) 主要是由婴儿莱什曼病引起的.
皮肤雷什曼病 (CL) 主要是由热带雷什曼病引起的.
新出现的L. tropica引起的VL病例表明流行病学正在发生变化.

研究的目的:

讨论L. tropica.内脏化背后的潜在机制.
描述内脏化L. tropica (VLT) 病例的临床方面.
评估土耳其L. tropica的内脏化所带来的公共卫生威胁.

主要方法:

七个由L. tropica引起的VL病例的回顾性分析.
临床数据收集包括症状和患者人口统计.
关于莱什曼病流行病学和潜在的L. tropica适应性的文献综述.

主要成果:

确定了7例与L. tropica相关的VL病例.
常见的症状包括发烧和壮症 (100%),疲劳和肝壮症 (86%),全细胞减肥 (86%),体重减轻和GIS症状 (71%).
患者主要是男性 (71%) 和成年人 (57%).

结论:

热带莱什马尼亚正在成为土耳其内脏莱什马尼亚病的原因,这对公众健康造成了重大关注.
潜在的内脏化机制包括遗传交换,药物诱导的压力和适应性进化.
进一步的研究至关重要,以了解VLT菌株的载体能力和循环,以减轻对土耳其和欧洲的威胁.

关键词:

皮肤上的莱什曼病.欧洲欧洲欧洲欧洲欧洲欧洲欧洲热带鱼 (Leishmania tropica) 是一个热带鱼.病变的发生和发病.土耳其土耳其土耳其土耳其土耳其土耳其土耳其土耳其土耳其内脏莱什曼病 - 内脏莱什曼病

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