在被切除的III期黑色素瘤成年人中偏好辅助免疫疗法-一个离散选择实验
Ann Livingstone1,2, Kirsten Howard3,4, Alexander M Menzies5,6,7
1Faculty of Health, Deakin Health Economics, Institute for Health Transformation, School of Health and Social Development, Deakin University, Burwood, VIC, Australia. a.livingstone@deakin.edu.au.
The patient
|June 23, 2023
概括
切除黑色素瘤的成年人更喜欢辅助免疫疗法,特别是当它减少复发风险和不良事件时. 患者对黑色素瘤治疗的偏好平衡了疗效,安全性和成本.
科学领域:
- 在瘤学瘤学.
- 医学经济学 医学经济学
- 行为科学 行为科学
背景情况:
- 辅助免疫疗法是切除黑色素瘤的治疗选择.
- 了解患者的偏好对于治疗决策和获得治疗至关重要.
研究的目的:
- 量化成年人对被切除黑色素瘤的辅助免疫治疗的偏好.
- 评估复发风险,不良事件和成本对治疗选择的影响.
主要方法:
- 对116名受访者进行了一项离散选择实验 (DCE).
- DCE包括诸如复发风险,不良事件和自付费用等属性.
- 一个混合多项逻辑模型分析了偏好和支付意愿.
主要成果:
- 70%的受访者选择辅助免疫疗法而不是没有辅助免疫疗法.
- 偏好有利于降低复发风险,减少永久性和致命性不良事件,降低成本.
- 愿意为降低风险付费的意愿因收入而异;受访者接受更多的AE,以降低复发风险.
结论:
- 大多数患者更喜欢辅助免疫疗法,当它提供更好的疗效和安全性.
- 这些发现可以为医疗保健政策提供有关黑色素瘤患者获得辅助免疫治疗的信息.
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