厄瓜多尔癌症患者的COVID-19死亡率和风险因素:一个回顾性,非随机的,受控的研究
Evelyn Valencia-Espinoza1, María Del Carmen Cabezas2, Andrea Plaza3
1Onco-hemathology Service, Hospital SOLCA Guayaquil, Guayaquil, Ecuador.
Medicine
|June 23, 2023
概括
COVID-19并没有增加癌症患者的死亡风险. 然而,高费里水平和机械通风被确定为在重症监护室患者中COVID-19死亡率的独立风险因素.
科学领域:
- 在瘤学瘤学.
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- COVID-19 流行病对医疗保健系统产生了重大影响,特别是影响了癌症等慢性病患者.
- 了解COVID-19癌症患者的特定风险和结果对于有效的临床管理至关重要.
研究的目的:
- 为了评估癌症患者的死亡率,风险因素和症状,与被诊断为COVID-19并入住重症监护室 (ICU) 的对照患者相比.
主要方法:
- 在厄瓜多尔的一个瘤中心进行了一项回顾性,观察性,非随机的,受控的研究.
- 分析了79名成年COVID-19ICU患者 (40名癌症患者,39名对照患者) 的数据,使用描述性统计和后勤回归.
- 信息包括社会人口统计,临床病史,症状,实验室结果,COVID-19治疗和出院状态.
主要成果:
- 在癌症患者和对照人群之间没有观察到统计学上显著的死亡率差异.
- 癌症患者的血红蛋白水平较低,并且接受抗病毒治疗的频率低于对照组.
- 高费里水平 (AOR 3.9) 和机械通风 (AOR 4.9) 被确定为COVID-19死亡的独立风险因素.
结论:
- 在这个ICU队列中,COVID-19感染并没有增加癌症患者的死亡风险.
- 提高费里水平和需要机械通风的要求是COVID-19患者死亡率的重要预测因素.
- 进一步的研究可能会探索患有严重COVID-19的癌症患者的特定管理策略.
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