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Updated: Jul 25, 2025

An Orthotopic Murine Model of Human Prostate Cancer Metastasis
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普罗贝尼西德可以改善丸激素诱导的良性前列腺增生症:PGE-2对ADAM-17/EGFR/ERK1/2信号级联的影响

Maha M Abdel-Fattah1, Mohammed E Abo-El Fetoh2, Hassan Afify2

  • 1Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.

Journal of biochemical and molecular toxicology
|June 23, 2023
PubMed
概括

美国食品和药物管理局批准的痛风药物Pobenecid在治疗良性前列腺增生症 (BPH) 中表现有前途,通过减少前列腺大小和改善组织结构. 它充当COX-2抑制剂,抑制炎症并调节参与BPH发展的关键信号通路.

关键词:
在ADAM-17中,它是ADAM-17.在COX-2中,COX-2是最常见的.埃格弗-ERK1/21/2 的时间.在PGE2的基础上,PGE2良性前列腺增生症 良性前列腺增生症试验杀伤剂是一种杀伤剂.

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