2型糖尿病患者同时进行运动训练的有效性:系统性审查和元分析
Saima Zaki1, Saurabh Sharma1, Hemlata Vats1
1Centre for Physiotherapy and Rehabilitation Sciences, Jamia Millia Islamia, Maulana Mohammad Ali Jauhar Marg, New Delhi, India.
Physiotherapy theory and practice
|June 23, 2023
概括
同时运动训练 (CET) 显著改善了2型糖尿病患者的关键健康指标. 这种结合有氧和阻力运动的方法提高了新陈代谢控制,身体组成和心肺呼吸能力.
科学领域:
- 运动生理学 运动生理学
- 代谢疾病 代谢疾病
- 运动医学 运动医学
背景情况:
- 同步运动训练 (CET) 在同一训练中结合有氧和抵抗运动.
- 关于CET对2型糖尿病 (T2DM) 的影响需要进一步阐明.
- 现有研究对CET在T2DM管理中的有效性提出了不确定的发现.
研究的目的:
- 在T2DM患者中,系统地审查和元分析CET对代谢标记,身体组成,脂质概况,炎症和心肺呼吸能力 (CRF) 的影响.
- 综合目前关于CET对T2DM患者的益处的证据.
- 提供CET对T2DM中各种健康参数的影响的全面概述.
主要方法:
- 在2023年1月之前,对五个电子数据库进行了系统搜索.
- 纳入标准包括对T2DM参与者 (35-65岁) 进行前性研究,每周至少两次进行CET,至少8周,与对照组进行.
- 最初确定了七项研究;由于一项研究的数据限制,对六项研究进行了元分析.
主要成果:
- 在葡萄糖水平 (p < .01),糖化血红蛋白 (p = .02) 和胰岛素抵抗 (p = .02) 中观察到显著改善.
- CET对身体组成产生了积极的影响,包括减少体质指数 (p = .02),体脂百分比 (p < .01),腰围 (p = .03),同时增加无脂肪质量 (p < .01).
- 此外,在脂质样本 (甘油三,p < .01),心肺呼吸能力 (氧气吸收峰值,p < .01) 和炎症标志物 (瘤缩因子-α,p < .01) 中也注意到了改善.
结论:
- 同时运动训练 (CET) 是一种有效的干预措施,用于改善T2DM患者的代谢标记,身体组成,脂质样本,炎症和心肺健康状况.
- 可以安全地将CET纳入2型糖尿病管理策略中.
- 支持这些结论的证据的整体强度可能会受到包含的研究中的潜在偏见的影响.
相关概念视频
Carbohydrate Metabolism
11.3K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.3K
Diabetes Mellitus: Type 2 and Gestational
2.6K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.6K
Exercise and Cardiovascular Response
870
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
870
Diabetes Mellitus: Overview and Type I Subtype
2.8K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.8K
Diabetes: Management and Pharmacotherapy
319
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
319
Oral Hypoglycemic Agents: Biguanides and Glitazones
240
Biguanides, particularly metformin (Glucophage), are insulin sensitizers that enhance glucose uptake, thereby reducing insulin resistance. Unlike sulfonylureas, metformin doesn't prompt insulin secretion, which helps to curb hypoglycemia risk. Metformin is beneficial in treating conditions like polycystic ovary syndrome due to its insulin-resistance reduction capability. The drug's primary action involves curtailing hepatic gluconeogenesis, a significant contributor to high blood...
240


