过和唐氏综合征的发生
Aanchal Sharma1, Nicole Baumer2, Marilyn Augustyn3
1Division of Developmental Medicine, Boston Children's Hospital, Boston, MA.
概括
患有唐氏综合征和智力障碍的儿童在食欲调节和体重管理方面面临重大挑战. 行为干预措施显示中度成功,但持续的过度饮食仍然是这些人的关注点.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 发育障碍 发育障碍是一种发展障碍.
- 行为健康 行为健康
背景情况:
- 唐氏综合征和智力障碍与肥胖和饮食挑战的风险增加有关.
- 两个案例说明了影响唐氏综合征儿童食欲和体重的遗传,行为和环境因素的复杂相互作用.
- 早期食困难和以后出现的过度体重增加是常见的担忧.
研究的目的:
- 描述两个患有唐氏综合征和智力障碍的儿童管理食欲和体重的挑战.
- 评估各种行为和药理干预措施的有效性.
- 为了突出食欲调节的持续困难,尽管干预措施.
主要方法:
- 病例研究方法详细介绍了两个儿科患者的临床病史,行为干预和药物试验.
- 干预措施包括行为疗法,代币经济,饮食计划,应对技能培训和兴奋剂/α-agonist药物.
- 随着时间的推移,评估身体质量指数 (BMI) 和Z分数.
主要成果:
- 两位患者表现出持续的过度进食和显著的体重增加,尽管多次干预.
- 行为策略提供了间歇性的成功,挑战经常重新出现.
- 药物干预在控制食欲方面表现出有限的有效性,其中一个案例表明寻找食物行为的潜在恶化.
结论:
- 控制唐氏综合征和智力障碍儿童的食欲和体重是复杂的,通常需要多方面的长期策略.
- 行为干预非常重要,但可能需要持续适应.
- 需要进一步的研究,以确定更有效的治疗方法,对食欲调节障碍在这个人群.
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