周产期艾滋病毒暴露和感染以及护理人员抑郁症状
Sarah K Brewer1, Nicole Talge1, Claudia Holzman1
1Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, USA.
AIDS care
|June 23, 2023
概括
在乌干达,患有周围艾滋病毒感染但没有感染的儿童的照顾者报告的抑郁症状高于患有艾滋病毒感染的儿童的照顾者. 这突显了CPHEU小组中未得到满足的心理健康需求.
科学领域:
- 全球健康 全球健康
- 儿童传染病 儿童传染病
- 心理健康研究 心理健康研究
背景情况:
- 经产期接触或感染艾滋病毒 (CPHIV) 的儿童可以在后组合抗逆转录病毒疗法时代生存.
- 照顾者心理健康显著影响儿童发育,但在艾滋病毒流行环境的研究尚未充分探索所有艾滋病毒暴露/感染群体的这一点.
- 了解护理人员的心理健康对于艾滋病毒影响儿童的福祉至关重要.
研究的目的:
- 为了在乌干达与患有围产期获得的艾滋病毒感染 (CPHIV) 的儿童的照顾者之间比较抑郁症状,与没有感染的围产期艾滋病毒暴露 (CPHEU) 和没有艾滋病毒暴露或感染 (CHUU).
- 为了确定影响这些独特的儿科艾滋病毒群体的护理人员抑郁症状的因素.
- 为了解决影响儿童成长能力的因素的识别对公共卫生的重要性.
主要方法:
- 在乌干达进行了一项比较研究,涉及3组6-10岁儿童的照顾者:CPHIV (n=102),CPHEU (n=101) 和CHUU (n=103).
- 使用霍普金斯症状检查表来评估抑郁症状.
- 为了估计群体平均差异,采用了通用线性模型,调整后的模型包括照顾者人口统计,社会支持和终身创伤.
主要成果:
- 与患有围产期艾滋病毒感染 (CPHIV) 的儿童的护理人员相比,患有围产期艾滋病毒感染但没有感染 (CPHEU) 的儿童的护理人员报告了明显更高的抑郁症状.
- 在调整共变量后,这种差异仍然存在,并且在生物学母亲中仍然显著.
- 与CPHIV护理人员相比,CPHEU护理人员的较低社会支持和财富水平与更高的抑郁症状有关.
结论:
- 周产期艾滋病毒暴露但没有感染 (CPHEU) 的儿童的照顾者之间存在未满足的心理健康需求.
- 针对性的心理健康支持对于CPHEU的护理人员来说至关重要,以促进儿童的福祉.
- 进一步的研究应该调查在这个脆弱的照顾者群体中导致更高抑郁率的具体因素.
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