用左心室辅助装置支持患者的胃肠道出血:从桥梁到目的地的旅程
Mohamed Salah Mohamed1, Ahmed Shehadah1, Anas Hashem1
1Department of Internal Medicine, Rochester General Hospital, Rochester, New York.
The American journal of cardiology
|June 23, 2023
概括
胃肠道出血 (GIB) 影响15-25%的左心室辅助器件 (LVAD) 患者. 了解GIB机制和实施多学科管理策略对于改善患者的治疗结果至关重要.
科学领域:
- 心脏病学 心脏病学
- 胃肠病学 胃肠病学
- 医疗器械 医疗器械
背景情况:
- 末期心力衰竭是美国死亡的主要原因之一.
- 左心室辅助器件 (LVAD) 对于心力衰竭管理至关重要,但存在风险.
- 胃肠道出血 (GIB) 是LVAD患者的一个显著不良事件.
研究的目的:
- 审查LVAD接受者GIB的发病率,病理生理学,预测因素,诊断,管理和预防.
- 在先进的心力衰竭治疗的背景下,综合当前关于GIB的知识.
主要方法:
- 对LVAD患者GIB研究的综合文献综述.
- 分析报告的发病率,机制,诊断方法和治疗策略.
- 对预防措施和新兴技术的评估.
主要成果:
- 在LVAD患者中,GIB发病率在15%至25%之间.
- 潜在的机制包括动脉静脉形形,凝血病和抗血栓治疗.
- 上部GIB是最常见的;管理涉及血液动力学支持,抗血栓性调整和内镜/放射性干预.
结论:
- 及时诊断和多学科管理对于LVAD患者的GIB至关重要.
- 预防性药物可以通过向动脉静脉形形来降低GIB风险.
- 需要进一步研究风险分层和最佳的抗血栓策略.
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