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Updated: Jul 25, 2025

Generating a Reproducible Model of Mid-Gestational Maternal Immune Activation using PolyI:C to Study Susceptibility and Resilience in Offspring
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怀孕的复杂性:支持怀孕对多发性硬化症结果的持久影响的生物学机制

Maria Pia Campagna1, Jeannette Lechner-Scott2, Vicki E Maltby2

  • 1Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.

Autoimmunity reviews
|June 23, 2023
PubMed
概括

怀孕可能为患有多发性硬化症 (MS) 的女性提供长期益处. 研究表明,怀孕与延迟MS发病和减少残疾进展有关,可能是通过持久的免疫系统变化.

关键词:
出生 出生 出生 出生 出生 出生 出生 出生通过DNA甲基化.表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.免疫系统的免疫系统.神经生物学 神经生物学 神经生物学的平价性.

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Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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