视觉功能障碍是帕金森病中术后痴呆症的危险因素
Chao Li1, Cheng Lian1, Qian-Qian Wu1
1Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan, China.
World neurosurgery
|June 23, 2023
概括
视力障碍增加了经过深度大脑刺激 (DBS) 的帕金森病患者手术后妄 (POD) 的风险. 视力受损者需要在DBS手术后进行更密切的监测,因为POD发病率较高.
科学领域:
- 神经科学是一个神经科学.
- 眼科医生 眼科 眼科
- 老年病的医生 老年病的医生
背景情况:
- 帕金森病 (PD) 影响全球数百万人.
- 深度大脑刺激 (DBS) 是PD的常见治疗方法.
- 手术后妄 (POD) 是神经外科手术后的一个重大问题.
研究的目的:
- 为了确定DBS后帕金森病患者中POD的发病率.
- 为了确定影响这个人群中POD发展的因素.
主要方法:
- 评估了272名接受DBS治疗的帕金森病患者.
- 使用VIPD-Q和神经眼科检查来评估视觉功能.
- 追溯分析将视力障碍,RNFL厚度和VPA与POD患病率相关联.
主要成果:
- 在23.9%的患者中发生POD.
- 视力障碍 (VIPD-Q > 6) 显著增加了POD风险 (P < 0.001).
- RNFL厚度和VPA也与POD风险有关;植入点和麻醉时间并非如此.
结论:
- 视觉功能障碍与PD患者在DBS后增加POD风险密切相关.
- 视力受损的PD患者需要加强术后监测以减轻POD.
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