在西班牙的心血管二次预防中,CNIC-Polypill与单独的单组件相比的成本效益
A González-Domínguez1, A Durán1, Á Hidalgo-Vega2
1Fundación Weber, Madrid, Spain.
Revista clinica espanola
|June 23, 2023
概括
在西班牙,CNIC-Polypill战略显著改善了二次心血管预防,以更低的成本提供更多的寿命和质量调整的寿命. 这种多药剂方法是西班牙国家医疗保健系统的成本节约策略.
科学领域:
- 预防心血管疾病 预防心血管疾病
- 卫生经济学 卫生经济学
- 药物经济学 药物经济学
背景情况:
- 心血管疾病仍然是西班牙的主要死亡原因,需要有效的二次预防策略.
- 目前的治疗模式涉及单独的单元组件,有可能提高附着性和成本效益.
研究的目的:
- 评估CNIC-Polypill战略的成本效益与西班牙心血管事件二次预防的单独单元组件的成本效益.
- 确定CNIC-Polypill战略是否为西班牙国家医疗保健系统提供了节省成本的方法.
主要方法:
- 开发了一种马尔科夫成本效益模型,模拟了1000名二次预防患者的队列.
- 关于有效性,流行病学,成本和公用事业的数据来源于NEPTUNO研究,官方数据库和文献.
- 通过获得的寿命年 (LY) 和质量调整后的 LY (QALY) 评估了成本效益,并进行了灵敏度分析.
主要成果:
- 与单一组件相比,CNIC-Polypill策略带来了更大的LY (13.22) 和QALY (11.64) 收益.
- 发现CNIC-Polypill策略占主导地位,每名患者节省了280.68欧元.
- 概率灵敏度分析表明,82.4%的模拟低于每QALY获得的25,000欧元的门.
结论:
- 在西班牙,CNIC-Polypill战略是二次心血管疾病预防的成本效益高的方法.
- 实施CNIC-Polypill战略代表了西班牙国家医疗保健系统的成本节约措施.
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