精神障碍,参与和发展轨迹在丹麦结肠直肠癌计划:一个基于人口的队列研究
Mette Kielsholm Thomsen1, Marie Dahl Jørgensen2, Lars Pedersen2
1Department of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark; CASTLE - Cancer Survivorship and Treatment Late Effects, Department of Oncology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.
患有精神障碍的人在结直肠癌查中的参与率较低,尽管死亡率增加. 医疗保健提供者的支持可能会提高这一群体的查率.
科学领域:
- 公共卫生 公共卫生
- 在瘤学瘤学.
- 精神病学是一个精神病学.
背景情况:
- 与普通人群相比,患有精神障碍的人患结直肠癌的死亡率更高.
- 结肠直肠癌的发病率在患有和没有精神障碍的人之间是相似的.
研究的目的:
- 评估精神障碍患者在有组织的结直肠癌查计划中的参与率.
- 根据精神疾病的严重程度,识别查参与的差异.
主要方法:
- 一项以人口为基础的队列研究包括丹麦居民,年龄在50-74岁之间,被邀请在2014年至2018年期间进行两年一次的便免疫化学测试 (FIT).
- 根据精神疾病史 (没有,轻度/中度,严重) 分析参与率,查结果和随访结肠镜守率,使用了国家注册表数据.
- 调整后的参与差异和比例是使用伪观测方法计算的.
主要成果:
- 与没有精神障碍的人相比,患有轻度/中度精神障碍 (男性: -4.4 pp;女性: -3.8 pp) 和严重精神障碍 (男性: -13.8 pp;女性: -15.4 pp) 的人在结直肠癌查中的调整参与率较低.
- 患有精神障碍的人群中,FIT结果呈阳性的比例较高,结肠镜检查的坚持率较低,结肠镜检查不完整的比例更高.
结论:
- 患有精神障碍的人不太可能参加结直肠癌查.
- 干预措施,可能涉及全科医生或精神卫生机构,可以加强查参与.
- 建议根据心理障碍的类型提供量身定制的支持,以解决参与差距.
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