对于急性骨髓性白血病的心脏瘤学和移植
1Atrium Health, Sanger Heart & Vascular Institute, 1237 Harding Place, Suite 5200, Charlotte, NC, 28203, USA.
Best practice & research. Clinical haematology
|June 23, 2023
概括
全基性造血细胞移植 (HCT) 为高风险的急性髓性白血病 (AML) 提供了治疗方法. 心脏瘤学合作对于在接受HCT的AML患者中管理心血管风险和心脏毒性至关重要.
科学领域:
- 血液学 血液学 血液学
- 心脏病学 心脏病学
- 在瘤学瘤学.
背景情况:
- 全基性造血细胞移植 (allo-HCT) 是高风险急性髓性白血病 (AML) 的重要治疗选择.
- 心血管疾病在alo-HCT期间和之后具有显著的竞争风险,有助于发病率和死亡率.
- 越来越多的老年AML患者患有并发症,需要专门的心血管护理.
研究的目的:
- 突出心脏瘤学在管理与AML的allo-HCT相关的心血管并发症方面的关键作用.
- 强调血液学/瘤学和心脏病专家之间需要多学科合作.
- 在先进的 allo-HCT 技术的背景下,应对心血管共同疾病日益增长的挑战.
主要方法:
- 审查AML和allo-HCT当前的治疗模式.
- 在allo-HCT接受者中分析心血管风险和心脏毒性.
- 讨论心脏瘤学在癌症护理中的原则和益处.
主要成果:
- 心血管疾病是接受allo-HCT的AML患者的结果的主要决定因素.
- 心脏瘤学为优化心血管健康和管理治疗相关心脏毒性提供了一个框架.
- 移植人口老龄化,并增加了并发症,这凸显了综合护理的重要性.
结论:
- 与心脏瘤专家的密切合作对于接受allo-HCT的AML患者来说,从诊断到生存至关重要.
- 积极的心血管风险评估和管理对于改善alo-HCT结果至关重要.
- 心脏瘤服务的整合对于解决心血管疾病AML患者的复杂需求至关重要.
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