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Updated: Jul 25, 2025

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人类TRPV4与GTPase RhoA复合体中的结构

Kirill D Nadezhdin1, Irina A Talyzina1,2, Aravind Parthasarathy3

  • 1Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, 10032, USA.

Nature communications
|June 23, 2023
PubMed
概括

研究人员揭示了TRPV4-RhoA复合体的结构,详细介绍了RhoA如何调节TRPV4活性. 这一发现提供了对疾病机制和TRPV4相关疾病的潜在药物点的见解.

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