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Updated: Jul 25, 2025

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TRPV4-Rho GTPase复杂结构揭示了关门和疾病的机制

Do Hoon Kwon1, Feng Zhang1, Brett A McCray2

  • 1Department of Biochemistry, Duke University School of Medicine, Durham, NC, 27710, USA.

Nature communications
|June 23, 2023
PubMed
概括

结构洞察力揭示了RhoA如何调节TRPV4离子通道. 破坏这种相互作用会导致神经肌肉疾病,为TRPV4相关疾病提供新的治疗点.

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