在结核病治疗期间管理不良反应的临床标准
K P Singh1, A C C Carvalho2, R Centis3
1Department of Infectious diseases, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia, Victorian Infectious Disease Unit, Royal Melbourne Hospital, VIC, Australia.
概括
结核病 (TB) 治疗的不良影响可以通过新的临床标准来最大限度地减少. 这些指导方针促进了诊断和管理副作用的最佳实践,改善了患者的治疗结果和治疗坚持.
科学领域:
- 公共卫生 公共卫生
- 临床医学 临床医学
- 药物监督 药物监督 药物监督
背景情况:
- 结核病 (TB) 治疗期间的不良反应 (AE) 导致患者的显著发病率,死亡率和治疗中断.
- 建立明确的临床标准对于优化这些不良事件的诊断和管理至关重要.
研究的目的:
- 开发和提出基于证据的临床标准,用于诊断和管理结核病治疗相关的不良影响.
- 鼓励参与结核病护理的医疗保健专业人员采用最佳实践.
主要方法:
- 进行了德尔菲过程,涉及65名受邀专家.
- 专家们使用5点的利克特级来评估和评分临床标准草案.
主要成果:
- 针对结核病治疗的AE管理,确定了八项基于共识的临床标准.
- 标准涵盖治疗前咨询,风险因素评估,AE评估,护理提供,再挑战协议,医疗保健工作人员培训,新药监测和对知识差距的研究.
结论:
- 开发的标准提供了一个以人为中心,共识驱动的框架,以减轻结核病治疗期间不良影响的影响.
- 这些标准的实施旨在提高患者安全和结核病治疗完成率.
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