在全身性硬化症患者的全膝关节整形术后,并发症的增加率
Elizabeth Driskill1, Zhichang Zhang1,2, Jialun Chi1
1Department of Orthopaedic Surgery, University of Virginia, Charlottesville, VA, 22908, USA.
International orthopaedics
|June 24, 2023
概括
系统性硬化症 (SSc) 患者在全膝关节整形术 (TKA) 后面临更高的医疗和手术并发症风险. 这包括增加伤口并发症,中风和心脏病发作的可能性,需要仔细考虑TKA程序.
科学领域:
- 整形外科手术 整形外科手术
- 类风湿病学 类风湿病学
- 患者安全 患者安全
背景情况:
- 系统性硬化症 (SSc) 患者的全膝关节整形术 (TKA) 后的结果没有得到充分记录.
- 系统性硬化症 (SSc) 是一种自身免疫性疾病,可以影响多个器官系统.
研究的目的:
- 评估全身性硬化症 (SSc) 作为膝关节全关节整形术 (TKA) 后并发症增加的风险因素.
- 为了比较接受TKA的SSc患者的并发症率与匹配的对照组.
主要方法:
- 对PearlDiver Mariner数据库的回顾性审查确定了2,002名接受初级TKA的SSc患者.
- 这些患者与19892名没有SSc.的对照进行了匹配.
- 多变量后勤回归分析了医疗并发症 (90天) 和手术并发症 (2年),包括急诊室访问和再入院.
主要成果:
- 患有SSc的患者表现出明显更高的医学并发症率,包括脑血管事故 (1.5%vs0.6%),心肌梗塞 (1.3%vs0.3%) 和败血症 (1.1%vs0.4%).
- 在SSc患者中,手术并发症也增加,特别是伤口并发症 (3.9%对2.2%) 和无菌松动90天,1年和2年.
- 在SSc组中,急诊室的访问频率更高 (21.2%对11.4%).
结论:
- 患有全身性硬化症 (SSc) 的患者经历TKA后的医疗和手术并发症的风险更高.
- 具体来说,SSc患者的伤口并发症,脑血管事故和心肌梗塞的可能性显著增加.
- 整形外科医生和患者在为SSc患者计划TKA时必须考虑这些高风险.
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