贫血与糖化血红蛋白之间的相关性 优糖 2 型糖尿病患者
Meenaxi Sharda1, Nikhil Gandhi2, Dharmendra Bansal2
1Senior Professor.
The Journal of the Association of Physicians of India
|June 24, 2023
概括
贫血常见于2型糖尿病患者,并影响糖化血红蛋白 (HbA1c) 水平. 即使控制了血糖,贫血也会导致HbA1c值升高,影响糖尿病管理.
科学领域:
- 内分泌学 在内分泌学.
- 血液学 血液学 血液学
背景情况:
- 糖尿病和贫血是印度普遍存在的健康问题.
- 糖化血红蛋白 (HbA1c) 对于DM诊断和监测至关重要.
- 贫血可能会影响HbA1c水平,需要在糖尿病患者中进行调查.
研究的目的:
- 为了确定患有2型糖尿病患者的贫血的发病率和类型.
- 分析HbA1c,红细胞 (RBC) 指数和贫血之间的相关性.
- 评估贫血对控制血糖的患者HbA1c的影响.
主要方法:
- 一项涉及2型糖尿病患者的横截面研究,患者在3个月内控制血糖.
- 纳入标准侧重于血糖水平稳定 (FBS 80-130 mg/dL,PP2BS <180 mg/dL) 的患者.
- 排除标准删除了患有特定疾病的患者,如血液溶解性贫血,慢性脏病和维生素B12缺乏症.
主要成果:
- 在被研究的糖尿病人群中,贫血患病率为56.8%.
- 常态细胞性常态色素性贫血是最常见的类型 (48.86%).
- 贫血患者的 HbA1c 中位数显著更高 (p <0.01) 和 Hb,红细胞指数 (MCH,MCV) 和 HbA1c 之间的负相关性.
结论:
- 贫血在2型糖尿病患者中很常见,即使没有脏病发作,也很常见,正常细胞性正常色素性贫血是最常见的.
- 贫血严重影响HbA1c水平,尽管控制了血糖.
- 这些发现强调了在糖尿病患者的HbA1c解释中考虑贫血的重要性.
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