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Updated: Jul 25, 2025

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状体mGlu5介导的突触可塑性是由特定位置的受体池和不同的信号通路独立调节的

Yuh-Jiin I Jong1, Yukitoshi Izumi2, Steven K Harmon1

  • 1Department of Neuroscience, Washington University School of Medicine, St Louis, Missouri, USA.

The Journal of biological chemistry
|June 24, 2023
PubMed
概括

细胞内和细胞表面的甲基增生性谷氨酸受体5 (mGlu5) 激活不同的通路. 细胞内mGlu5独特地驱动蛋白质降解和合成,影响突触可塑性和长期抑郁.

关键词:
G蛋白结合受体 (GPCR) 是一种和是最重要的.细胞外信号调节激酶 (ERK) 的作用.mTOR复合体 (mTORC) 是一个复合体.甲基氨酸受体5 (mGlu(5)) 的甲基氨酸受体神经元神经元的神经元信号传导的信号传导.

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