左心室功能和尺寸在婴儿早期发生变化 在新生儿脑病变的设置中发展脑损伤
Pierre Elias1, Anie Lapointe2, Pia Wintermark1
1Division of Neonatology, Montreal Children's Hospital, Montreal, QC, Canada; McGill University Health Centre - Research Institute, Montreal, QC, Canada.
The Journal of pediatrics
|June 24, 2023
概括
新生儿脑症脑损伤与特定的心脏功能变化有关. 三维回声心脏图显示,脑损伤的新生儿左心室体积更大,全球周围应力达到峰值.
科学领域:
- 心脏病学 心脏病学
- 新生儿科学 新生儿科学
- 神经科学是一个神经科学.
背景情况:
- 新生儿脑病变 (NE) 是新生儿的一种严重疾病.
- 脑损伤是NE的常见并发症.
- 早期发现脑损伤对于及时干预至关重要.
研究的目的:
- 为了研究左心3维回声心脏学参数与新生儿中NE脑损伤之间的关联.
- 确定潜在的回声心脏学标记,用于预测该人口中的脑损伤.
主要方法:
- 进行了一项单一中心前性研究.
- 包括被诊断为NE的新生儿.
- 在生命的第二天进行了三维回声心脏图,以评估心脏参数.
主要成果:
- 与没有脑损伤的新生儿相比,脑损伤的新生儿表现出左心室终端透支体积显著增加.
- 研究人员还发现,脑损伤的新生儿中,中风的体积也更大.
- 在脑损伤的新生儿中检测到高峰全球环形应变.
结论:
- 左心3维回声心脏学参数,包括心室体积和全球周围应变,与新生儿的脑损伤有关.
- 这些发现表明,心声回声学可能为新生儿脑损伤对心脏的影响提供有价值的见解.
- 进一步的研究是有必要的,以探索这些心声回声标记在管理NE的临床实用性.
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