低水平激光治疗对血友病患者抽取后血静的作用 - 一项前性队列研究
Monica Kelkar1, Mithilesh Kadanthode1, Sujata Mohanty1
1Department of Oral and Maxillofacial Surgery, Maulana Azad Institute of Dental Sciences, MAMC Complex, New Delhi, India.
概括
低水平激光疗法 (LLLT) 在血友病患者的牙提取后显著减少了出血时间. 这种疗法在这种高风险人群中提供了一种有前途的辅助方法,以实现血液静止.
科学领域:
- 牙科手术 牙科手术
- 血液学 血液学 血液学
- 生物医学工程 生物医学工程
背景情况:
- 血友病患者的牙提取带来了显著的出血风险.
- 目前的静脉动脉协议和因子替代可以进行门诊手术,但缺乏标准化的出血预防.
- 低水平激光疗法 (LLLT) 的静血潜力已知,但未在血友病患者中确立.
研究的目的:
- 评估LLLT作为补充剂在血友病患者抽取后血液静止的标准方案的疗效.
- 为了比较血液静止的时间,再出血率,以及在LLLT和标准护理之间需要额外的干预措施.
主要方法:
- 一项前性干预队列研究,涉及60名血友病A或B型患者进行牙提取.
- 患者被分为一个测试组 (标准方案+LLLT) 和一个控制组 (仅标准方案).
- 评估的结果包括血液静止的时间,再出血的发生率和 suturing,烧结或因子输液的要求.
主要成果:
- 与对照组相比,LLLT组的血液静止平均时间减少了22.42%.
- 在4例测试组病例和13例对照组病例中发生了再出血.
- 在LLLT组中,需要术后因子输注的患者较少 (3对12).
结论:
- 在血友病患者的牙提取后,LLLT的外科应用显著减少了血静所需的时间.
- 在这种人群中,LLLT显示出作为一种有价值的辅助疗法,用于管理出血风险的潜力.
- 需要进一步的研究来支持LLLT在血友病护理中的常规使用.
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