息性放射疗法用于恶性病的血液静止:一个系统性审查
1Division of Radiation Oncology, The Ottawa Hospital, Ottawa, Ontario, Canada.
概括
息性放射治疗有效地控制了晚期癌症的出血. 虽然更高的剂量和低分化有希望,但为了控制癌症出血的最佳结果,需要量身定制的治疗和进一步的研究.
科学领域:
- 在瘤学瘤学.
- 辐射瘤学 辐射瘤学
背景情况:
- 息性放射治疗是恶性瘤引起的出血的标准治疗方法.
- 有效的血液静止对于管理晚期癌症出血至关重要.
研究的目的:
- 评估息性放射治疗在控制恶性瘤诱导出血的疗效.
- 为了确定放射治疗在实现血液静止方面的证据水平.
主要方法:
- 对Medline,Embase和Cochrane数据库 (1947-2017) 的系统文献综述.
- 包括13项前性和45项后性研究,报告了放射治疗的定性或定量影响.
- 根据瘤类型分类的研究,以比较剂量和分量表.
主要成果:
- 结果报告中的显著差异和患者数量的少量阻止了定量分析.
- 较高的中位数剂量和低分量方案表明血静率数量上更高.
- 支臂疗法显示出有效性,特别是在妇科恶性瘤中.
结论:
- 息性放射疗法对于在晚期,无法治愈的恶性瘤中管理出血是有价值的.
- 治疗个性化是必不可少的,考虑到缓解目标.
- 建议进行进一步的前性研究,以确定最佳的剂量和分成方案.
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