振荡计脉冲波分析用于检测低流动的动脉静脉
Veit Busch1,2, Joachim Streis3,4, Sandra Müller5
1Nephrovital, Kamen, Germany. veit.busch@web.de.
BMC nephrology
|June 24, 2023
概括
方便的振荡计仪器可以评估血液透析患者的动脉静脉的功能. 相对体积变化 (AMP) 参数的幅度在检测低流量时显示出最高的准确性.
科学领域:
- 血管接入监测 血管接入监测
- 血液透析技术 血液透析技术
- 心血管诊断心血管诊断
背景情况:
- 动脉静脉 (AVF) 功能对于血液透析的有效性至关重要.
- 脉冲波分析 (PWA) 显示了对非侵入性抽评估的潜力.
- 需要方便的方法来检测减少流量 (<500毫升/分钟).
研究的目的:
- 为了前性地评估用于AVF功能评估的振荡计设备.
- 为了确定PWA在现实临床环境中的适用性.
- 为了确定能够检测低流的PWA参数.
主要方法:
- 这是一项前性研究,涉及53名血液透析患者,这些患者有原生AV囊.
- 脉冲波记录使用vicorder®装置在臂动脉.
- 对脉冲波参数的分析:斜率2,斜率和振幅 (AMP);通过双重超声波测量状管流.
主要成果:
- 振荡计参数区分了和非臂测量,具有显著的灵敏度和特异性.
- ROC分析表明,AMP (AUC=0.775) 和Slope (AUC=0.732) 可以检测到低流.
- AMP表现出最高的诊断准确性,最佳切断值产生93%的灵敏度和78%的特异性来检测低流量.
结论:
- 使用振荡计对AV的功能监测是一种有前途的临床工具.
- 来自PWA的振幅 (AMP) 参数为识别减少流提供了最高的诊断准确性.
- 振荡计装置提供了一种方便和有效的方法,用于监测血液透析中AV的功能.
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